Nervous System: Neuronal Network
I am not a linguist, I am a biologist. Therefore, I shall speak about language as a biologist, and address myself to two basic biological questions, namely:
This is my way of honoring the memory of Eric H. Lenneberg, if one honors the memory of another scientist by speaking about one's own work Whatever the case, I wish to honor his memory not only because of his great accomplishments, but also because he was capable of inspiring his students, as the symposium on which this book is based revealed. The only way I can do this is to accept the honor of presenting my views about biology, language, and reality.
I shall, accordingly, speak about language as a biologist. In doing so, I
shall use language, notwithstanding that this use of language to speak about language is within the core of the problem I wish to consider.
Since I am writing about language as a scientist attempting to address myself to the biological phenomena involved in its generation and use, I shall make the following epistemological assumptions in order to characterize the language I shall use.
We as scientists make scientific statements. These statements are validated by the procedure we use to generate them: the scientific method. This method can be described as involving the following operations: (a) observation of a phenomenon that, henceforth, is taken as a problem to be explained; (b) proposition of an explanatory hypothesis in the form of a deterministic system that can generate a phenomenon isomorphic with the one observed, (c) proposition of a computed state or process in the system specified by the hypothesis as a predicted phenomenon to be observed; and (d) observation of the predicted phenomenon.
In the first operation, the observer specifies a procedure of observation that, in turn, specifies the phenomenon that he or she will attempt to explain. In the second, the observer proposes a conceptual or concrete system as a model of the system that he or she assumes generates the observed phenomenon. In the third, the observer uses the proposed model to compute a state or a process that he or she proposes as a predicted phenomenon to be observed in the modeled system. Finally, in the fourth operation he or she attempts to observe the predicted phenomenon as a case in the modeled system. If the observer succeeds in making this second observation, he or she then maintains that the model has been validated and that the system under study is in that respect isomorphic to it and operates accordingly. Granted all the necessary constraints for the specification of the model, and all the necessary attempts to deny the second observations as controls, this is all that the scientific method permits.
This we all know. Yet we are seldom aware that an observation is the realization of a series of operations that entail an observer as a system with properties that allow him or her to perform these operations, and, hence, that the properties of the observer, by specifying the operations that he or she can perform determine the observer's domain of possible observations. Nor
are we usually aware that, because only those statements that we generate as observers through the use of the scientific method are scientific statements, science is necessarily a domain of socially accepted operational statements validated by a procedure that specifies the observer who generates them as the standard observer who can perform the operations required for their generation. In other words, we are not usually aware that science is a closed cognitive domain in which all statements are, of necessity, subject dependent, valid only in the domain of interactions in which the standard observer exists and operates. As observers we generally take the observer for granted and, by accepting his universality by implication, ascribe many of the invariant features of our descriptions that depend on the standard observer to a reality that is ontologically objective and independent of us. Yet the power of science rests exactly on its subject dependent nature, which allows us to deal with the operative domain in which we exist. It is only when we want to consider the observer as the object of our scientific inquiry, and we want to understand both what he does when he makes scientific statements and how these statements are operationally effective, that we encounter a problem if we do not recognize the subject dependent nature of science. Therefore, since I want to give a scientific description of the observer as a system capable of descriptions (language), I must take the subject dependent nature of science as my starting point.
As scientists, we want to provide explanations for the phenomena we observe. That is, we want to propose conceptual or concrete systems that can be deemed to be intentionally isomorphic to (models of) the systems that generate the observed phenomena. In fact, an explanation is always an intended reproduction or reformulation of a system or phenomenon, addressed by one observer to another, who must accept it or reject it by admitting or denying that it is a model of the system or phenomenon to be explained. Accordingly, we say that a system or a phenomenon has been scientifically explained if a standard observer accepts that the relations or processes that define it as a system or phenomenon of a particular class have been intentionally reproduced, conceptually or concretely.
Two basic operations must be performed by an observer in any explanation: (a) the specification (and distinction thereof) of the system (composite unity) or phenomenon to be explained; and (b) the identification and distinction of the components and the relations between components that permit the conceptual or concrete reproduction of the system or phenomenon to be explained. Since these two operations are not independent, when the ob-
server specifies a system or phenomenon to be explained he or she defines the domain in which it exists and determines the domain of its possible components and their relations; conversely, when the observer specifies the actual components and relations that he or she intends to use in the explanation, he or she determines the domain in which this will be given and in which the reproduced system will exist. Yet the kind of explanation that an observer accepts depends on his or her a priori criteria for the validation of his or her statements. Thus the observer may accept either a mechanistic or a vitalistic explanation.
In a mechanistic explanation, the observer explicitly or implicitly accepts that the properties of the system to be explained are generated by relations of the components of the system and are not to be found among the properties of those components. The same applies to the mechanistic explanation of a phenomenon, in which case the observer explicitly or implicitly accepts that the characteristics of the phenomenon to be explained result from the relations of its constitutive processes, and are not to be found among the characteristics of these processes. Contrariwise, in a vitalistic explanation, the observer explicitly or implicitly assumes that the properties of the system, or the characteristics of the phenomenon to be explained, are to be found among the properties or among the characteristics of at least one of the components or processes that constitute the system or phenomenon. In a mechanistic explanation the relations between components are necessary; in a vitalistic explanation they are superfluous. An example of a mechanistic explanation is: The weight of a body is the sum of the weight of its components. The relation sum, applied to the components as defined by their property weight, determines the property weight of the body. Example of a vitalistic explanation: Jacques Monod said in Le Hasard et la Nécessité (1970) "L'ultima ratio de toutes les structures et performances téléonomiques des être vivants est donc enfermée dans les sequences de radicaux des fibres polipeptidiques, 'embryons' de ces démons de Maxwell biologiques que vent le protéines globulaires. En un sense très réel c'est à ce niveau d'organization chimique que gît s'il y a en a un, le secre de la vie [p. 110]." [The ultima ratio of all telenomic structures and functions of living systems is, then, embeded in the amino acidic sequence of the polypeptide chains that truly constitute embryos of Maxwell's biological demons that are the globular proteins. It is at this level of chemical organization that in a very real sense lies, if there is any, the secret of life.] This statement answers the question -- What kinds of systems are living systems? -- by reference to the properties of one of their components.
In a mechanistic explanation the observer explicitly or implicitly distinguishes between a system and its components, treating the system and the components as operationally different kinds of unities that belong to disjoint
sets that generate nonintersecting phenomenic domains. The relation of correspondence between the phenomenal domain generated by a system and the phenomenal domain generated by its components, which an observer may assert after enuciating a mechanistic explanation, is, therefore, established by the observer through his or her independent interactions with the system and with its components and does not indicate a phenomenal reduction of one domain to another. If it appears as if there were a phenomenal reduction, it is because in the description all phenomena are represented in the same domain, and, unless care is taken to preserve it, the relation established through the observer is lost. The reality described through mechanistic explanations, then, implies the possibility of an endless generation of nonintersecting phenomenal domains as a result of the recursive constitution (organization) of new classes of unities through the recursive novel combinations of unities already defined. For epistemological reasons, then, mechanistic explanations are intrinsically nonreductionist.
With vitalistic explanations, the situation is the contrary: They do not distinguish between the phenomenal domain generated by a unity and the phenomenal domain generated by its components. The reality described through vitalistic explanations is, necessarily, a reality of a finite number of phenomenal domains. For epistemological reasons, then, vitalistic explanations are intrinsically reductionist.
defined as simple, the properties assigned to the unity by the operations of distinction that specify it are supposed to be constitutive, and no question about their origin arises. If the unity is defined as composite, it is assumed that it has components that may be specified through additional operations of distinction, and that it is realized as a unity by an organization that determines its properties through determining those relations between its components that specify the domain in which it can be treated as simple.
Organization and structure, therefore, are not synonyms. The organization of a system defines it as a composite unity and determines its properties as such a unity by specifying a domain in which it can interact (and, hence, be observed) as an unanalyzable whole endowed with constitutive properties. The properties of a composite unity as an unanalyzable whole establish a space in which it operates as a simple unity. In contrast, the structure of a system determines the space in which it exists as a composite unity that can be perturbed through the interactions of its components, but the structure does not determine its properties as an unity. An unanalyzable unity can be
designated by a name and identified by a concept that refers to the constellation of properties that define it, but it has no organization or structure. A simple unity has only a constellation of properties; it is a fundamental entity that exists in the space that these properties establish. it follows that spatially separated composite unities (systems) may have the same organization but different structures, and that a composite unity remains the same only as long as its organization remains invariant. Whenever the structure of an entity changes so that its organization as a composite unity changes, the identity of the entity changes and it becomes a different composite unity -- a unity of a different class to which we apply a different name. Whenever the structure of a composite unity changes and its organization remains invariant, the identity of the entity remains the same and the unity stays unchanged as a member of its original class; we do not change its name. It follows that whenever a system is to be explained, it is necessary and sufficient to reproduce its organization. Yet when a particular system is to be reproduced, both its organization and its structure must be reproduced.
These systems undergo only changes determined by their organization and structure that are either changes of state (defined as changes of structure without toss of identity) or disintegration (defined as changes of structure with loss of identity). For these systems it is necessarily the case that: (a) they may undergo only interactions that either perturb them by triggering in them structural changes that lead to changes of state or disintegrate them by triggering in them structural changes that lead to their loss of identity; (b) the changes of state they undergo as a result of perturbing interactions are not specified by the properties of the perturbing entities, which only trigger them; (c) the structural changes they undergo as a result of disintegrating interactions are not specified by the properties or the disintegrating entity, which only trigger them; and (d) their structure, by specifying which relations must arise between their components as a result of their interactions in order to initiate their triggered changes of state, specifies the configuration of properties that an entity must have in order to interact with them and operate either as a perturbing or as a disintegrating agent.
The organization and structure of a structure-determined system, therefore, continuously determine: (a) the domain of states of the system, by specifying the states that it may adopt in the course of its internal dynamics or as a result of its interactions; (b) its domain of perturbations, by specifying the matching configurations of properties of the medium that may perturb it; and (c) its domain of disintegration, by specifying all the configurations of properties of the medium that may trigger its disintegration.
If the state a system adopts as a result of an interaction were specified by the properties of the entity with which it interacts, then the interaction would be an instructive interaction. Systems that undergo instructive interactions cannot be analyzed by a scientific procedure. In fact, all instructable systems would adopt the same state under the same perturbations and would necessarily be indistinguishable to a standard observer If two systems can be distinguished by a standard observer, it is because they adopt different states under what he or she would otherwise consider identical perturbations and are not instructable systems. The scientific method allows us to deal only with systems whose structural changes can be described as determined by the relations and interactions of their components, and which, therefore, operate as structure-determined systems. Structure-determined systems do not undergo instructive interactions. In these circumstances, any description of an interaction in terms of instructions (or of information transfer) is, at best, metaphorical; it does not reflect the actual operation of the systems
involved as objects of scientific description and study. Consequently, every scientific assertion is a statement that necessarily implies a structure determined system proposed by the standard observer as a model of the structure-determined system that he or she assumes to be responsible for his or her observations. For epistemological reasons, then, scientific predictions are computations of state trajectories in structure determined systems, and chance or indeterminism enter in scientific assertions only as computational artifices used in models that assume object systems that cannot be observed in detail, not as a reflection of an ontological necessity.
For an observer, the organization and structure of a structure determined system determine both its domain of states and its domain of perturbations as collections of realizable possibilities. This is so because an observer can imagine, for any structure-determined system that he or she conceives or describes, different state trajectories arising from correspondingly different sequences of perturbations by imagining the system under different circumstances of interactions. Yet what in fact occurs during the ontogeny (individual history) of any particular structure-determined system is that the structure of the medium in which it interacts and, hence, exists, and which, in this respect, operates as an independent dynamic system even while changing as a result of the interactions, provides the actual historical sequence of perturbations that, in fact, selects which of the imaginable possible state trajectories of the system indeed takes place. If the structure of the medium that matches the domain of perturbations of the structure-determined system is redundant or recurrent, then the structure determined system undergoes recurrent perturbations; if the structure of the medium is in continuous change, then the structure-determined system undergoes continuously changing perturbations; finally, if the matching structure of the medium changes as a result of the operation of the structure determined system, then this system undergoes changingperturbations that are coupled to its own state trajectory. Now, if a structure determined system, as a result of its interactions, undergoes changes of state that involve structural changes in its components (and not only in their relations), then I say that the system has a second-order plastic structure, and that it undergoes plastic interactions. When this is the case, the plastic interactions that such a system undergoes select in it trajectories of second order structural changes that result in the transformation of both its domain of states and its domain of perturbations. The outcome of the continued interactions of a structurally plastic system in a medium with redundant or
recurrent structure, therefore, may be the continued selection in the system of a structure that determines in it a domain of states and a domain of perturbations that allow it to operate recurrently in its medium without disintegration. I call this process "structural coupling." If the medium is also a structurally plastic system, then the two plastic systems may become reciprocally structurally coupled through their reciprocal selection of plastic structural changes during their history of interactions. In such a case, the structurally plastic changes of state of one system become perturbations for the other, and vice versa, in a manner that establishes an interlocked, mutually selecting, mutually triggering domain of state trajectories.
Living systems are autonomous entities, even though they depend on a medium for their concrete existence and material interchange; all the phenomena related to them depend on the way their autonomy is realized. A perusal of present-day biochemical knowledge reveals that this autonomy is the result of their organization as systems in continuous self-production. This organization in terms of self-production can be characterized as follows.
There is a class of dynamic systems that are realized, as unities, as networks of productions (and disintegrations] of components that: (a) recursively participate through their interactions in the realization of the network of productions (and disintegrations) of components that produce them; and (b) by realizing its boundaries, constitute this network of productions (and disintegrations) of components as a unity in the space they specify and in which they exist. Francisco Varela and I called such systems autopoietic systems, and autopoietic organization their organization (Maturana & Varela, 1973). An autopoietic system that exists in physical space is a living system (or, more correctly, the physical space is the space that the components of living systems specify and in which they exist) (Maturana, 1975).
In this characterization of the organization of living systems, nothing is stipulated about their structure, which can be any form that satisfies it. Also, nothing is said about the medium in which an autopoietic system may exist, or about its interactions or material interchanges with the medium, which can be any that satisfy the constraints imposed by the actual structure through which the autopoiesis is realized. In fact, to the extent that an
autopoietic system is defined as a unity by its autopoiesis, the only constitutive constraint that it must satisfy is that all its state trajectories lead to autopoiesis; otherwise it disintegrates. Therefore, an autopoietic system, while autopoietic, is a closed dynamic system in which all phenomena are subordinated to its autopoiesis and all its states are states in autopoiesis. This conclusion has several fundamental consequences.
both phenomenal domains, however, the changes in the relations of the components appear as changes in state in the living system that modify its properties and, hence, its interactions in its environment -- all of which he or she describes by saying that the physiology of the organism generates its behavior. Yet, since these two phenomenal domains do not intersect, the relations that an observer may establish between the phenomena of one and the phenomena of the other do not constitute a phenomenal reduction, and the generative operational dependency of behavior on physiology that the observer asserts in this manner does not imply a necessary correspondence between them. Accordingly, in no particular case can the phenomena of one domain be deduced from the phenomena of the other prior to the observation of their actual generative dependency. The implicative relation that an observer can use a posteriori to describe an observed generative dependency existing between a particular behavior and a particular physiological phenomenon is necessarily contingent on the particular structure of the living system which, at the moment of observation, determines the changes of state that the observer sees as behavior. Therefore, the implicative relation used by the observer in his description is not a logical implication as would be the case if behavioral and physiological phenomena belonged to the same phenomenal domain. The result is that, in order to explain a given behavior of a living system, the observer must explain the generation and establishment of the particular structures of the organism and of the environment that make such behavior possible at the moment it occurs.
Ontogenic and evolutionary adaptations in living systems arise through the selection of the structures that permit the autopoiesis of the living system in the medium in which it exists. In both cases, selection takes place as a differential structural realization that results from the operational confrontation of systems endowed with independently determined domains of structural diversity and plasticity. In the case of the evolution all the structural diversity of living systems, available for selection is produced in them in parallel, through each reproductive step, as a result of their genetic properties, and the selection takes place as differential survival or differential
reproductive success. In the case of ontogenic changes, the structural diversity of living systems available for selection is present, at any instant, in the domain of perturbations of each living system, and selection takes place during the history of each individual according to the sequence of perturbations provided by the medium. No example of evolutionary selection is needed. As examples of ontogenic selection the following two are presently adequate:
Adaptation, then, is always a trivial expression of the structural coupling of a structurally plastic system to a medium. Adaptation always results from sequences of interactions of a plastic system in its medium that trigger in the plastic system structural changes or changes of state that, at any instant, select in it a structure that either matches (is homomorphic to) the structure of the medium in which it operates (interacts or behaves) as such a system, or disintegrate it. It follows that, in the operation of living systems as autopoietic unities in a medium, the coincidence between a given structure of the medium (place in the medium) and a given structure in the living system is always the result of the history of their mutual interactions, while both operate as independent, structurally determined systems. Furthermore, as a result of the structural coupling that takes place during such a history, history becomes embodied both in the structure of the living system and in the structure of the medium, even though both systems necessarily, as structure-determined systems, always operate in the present through locally determined processes. Therefore, although from the cognitive point of view adequate behavior as a case of adaptation cannot be understood without reference to history and context, from the operational point of view adequate behavior is only an expression of a structural matching in the present between organism and medium, in which history does not participate as an operative component. History is necessary to explain how a given system or phenomenon came to be, but it does not participate in the explanation of the operation of the system or phenomenon in the present.
The nervous system is a network of interacting neurons that generates a phenomenology of neuronal interactions subservient to the autopoiesis of the organism in which it is embedded and of which it is a component. Therefore, in order to explain the nervous system as a system, it is necessary and sufficient to point to the organization that defines a neuronal network that generates its phenomenology of neuronal interactions as a constitutive component of an autopoietic system, such as a metazoan.
Such organization can be described as follows. The nervous system is defined as a system (a unity) by relations that constitute it as a closed
network of interacting neurons such that any change in the state of relative activity of a collection of its component neurons always leads to a change in the state of relative activity of other (or the same collection of) neurons: All changes in relative neuronal activity in the nervous system always lead to other changes in relative neuronal activity in it. With respect to its dynamics of states, the nervous system is a closed system.A closed neuronal network does not have input or output surfaces as features of its organization, and, although it can be perturbed through the interactions of its components, for it, in its operation as a system, there are only states or changes of states of relative neuronal activity, regardless of what the observer may say about their origin. Given a closed system, inside and outside exist only for the observer who beholds it, not for the system. The sensory and effector surfaces that an observer can describe in an actual organism do not make the nervous system an open neuronal network, because the environment where the observer stands acts only as an intervening element through which the effector and sensory neurons interact, completing the closure of the network. This organization of the nervous system has several fundamental consequences.
by sequences of changes of state in its nervous system. Furthermore, the observer can, with no difficulty, describe any given behavior or conduct in purposeful (functional or semantic) terms that reflect the value or role that the observer ascribes to it in reference to the realization of the autopoiesis of the organism. Yet it is also apparent to the observer that, since the nervous system is a structure-determined system, the sequence of changing relations of relative neuronal activity that appears to him or her as determining a given behavior is not determined by any functional or semantic value that he or she may ascribe to such a behavior, but that, on the contrary, it is necessarily determined by the structure of the nervous system at the moment at which the behavior is enacted.
An example may clarify this situation. Let us consider what happens in instrumental flight. The pilot is isolated from the outside world; all he can do is manipulate the instruments of the plane according to a certain path of change in their readings. When the pilot comes out of the plane, however, his wife and friends embrace him with Joy and tell him: "What a wonderful landing you made; we were afraid, because of the heavy fog." But the pilot answers in surprise: "Flight? Landing? What do you mean? I did not fly or land; I only manipulated certain internal relations of the plane in order to obtain a particular sequence of readings in a set of instruments." All that took place in the plane was determined by the structure of the plane and the pilot, and was independent of the nature of the medium that produced the perturbations compensated for by the dynamics of states of the plane: flight and landing are irrelevant for the internal dynamics of the plane. However, from the point of view of the observer, the internal dynamics of the plane results in a flight only if in that respect the structure of the plane matches the structure of the medium; otherwise it does not, even if in the nonmatching medium the internal dynamics of states of the plane is indistinguishable from the internal dynamics of states the plane under observed flight. It follows that since the dynamics of states of an organism, or of a nervous system, or of any dynamic system, is always determined by the structure of the system, adequate behavior is necessarily only the result of a structural matching between organism (dynamic system) and medium.
have for the realization of the autopoiesis of a given organism in its medium is the result of the structural coupling existing between the nervous system and the organism, and between these and the medium.
The argument for structural coupling of autopoietic systems can be summarized as follows. Given that the interactions of a composite unity in the space of its components are interactions through its components (that is, are structural interactions), if, as a result of a structural interaction, the components of a unity or their relations change, the structure of the unity changes and, if this structural change occurs without a change in the organization of the composite unity, the identity of the unity remains invariant. A composite unity whose structure can change while its organization remains invariant is a plastic unity, and the structural interactions under which this invariance can be sustained are perturbations. Since it is a constitutive feature of an autopoietic system to maintain homeostatically invariant its organization under conditions of structural charge, the realization of the autopoiesis of a plastic living system under conditions of perturbations generated by a changing medium must result in the selection of a structure in the living system that incorporates, in its autopoietic network, specific processes (changes of state) that can be triggered by specific changes of state of the medium; otherwise, the system disintegrates. The result of establishing this dynamic structural correspondence, or structural coupling, is the effective spatiotemporal correspondence of the changes of state of the organism to the recurrent changes of state of the medium, while the organism remains autopoietic.
The same general argument can be applied to the nervous system in particular. The organization of the nervous system as a closed network of interacting neurons must remain invariant, but its structure may change if it is coupled to the structural change of other systems in which it is embedded, such as the organism, and through this, the medium in which the organism exists as an autopoietic unity, or, recursively, itself. If the structure of the nervous system changes, the domain of possible states of relative neuronal activity of the nervous system changes, and, hence, the domain of possible behavioral states of the organism itself changes, too. Therefore, if as a result of the structural changes of the nervous system the organism can go on in autopoiesis, the nervous system's changed structure may constitute the basis for a new structural change, which may again permit it to go on in autopoiesis. In principle, this process may be recursively repeated endlessly throughout the life of an organism.
That the ontogenic structural coupling of the nervous system to the organism, to the medium, and to itself should occur through recursive selective interactions is an epistemological necessity. Which interactions select which structural change in a particular nervous system depends on the
particular case under consideration. There are well-documented examples that I will not describe, but I will add that to the extent that the nervous system operates as a closed neuronal network its actual operation in the domain of relations of relative neuronal activities could not lead in it to second-order structural changes. However, since, in addition to their participation in the closed neuronal network that the nervous system is, neurons exhibit properties common to all other cells, neurons can be perturbed chemically or physically by the products of other cells of the organism, whether or not they are members of the nervous system, or of the medium. These perturbations, which are operationally orthogonal to the domain of relations of neuronal activities in which the nervous system operates, may trigger structural changes in the neurons that result in second order structural changes in the nervous system that result in changes in its domain of states that result (for the observer) in changes in behavior. Since these orthogonal perturbations constitute selective interactions, structural selection must take place through them in the domain of potential structural diversity constituted by the domain of perturbations of the organism, and it must take place through the spatial and temporal concomitances of chemical and physical neuronal perturbations determined by the structure of the media in which the nervous system is embedded. At this point it should be apparent that the only structure of the nervous system that allows for this sort of structural change is that in which the nervous system operates as an homeostatic closed neuronal network that generate, and maintains invariant relations of relative neuronal activity that are selected, through interactions orthogonal to this domain of operation, by the actual realization of the autopoiesis of the organism that it integrates.
While autopoiesis lasts, (a) continued ontogenic structural coupling of the nervous system selects the neuronal network structure that generates the relations of relative neuronal activity that participate in the continued autopoiesis of the organism in the medium to which it is coupled; and (b) the structural coupling of the nervous system to the organism, to its medium, or to itself that adequate behavior (interactions without disintegration) reveals may appear to an observer as a semantic coupling, because he or she can ascribe functional significance or meaning to any behavior, and can describe the underlying physiology as if caused by these semantic relations.
developmental process and not as a result of the history of its interactions as an individual. Any behavior that an observer may detect in an organism determined by a dynamics of states dependent on structures acquired by the species during evolution will be called instinctive behavior by the observer. If the structural coupling of the organism to its medium takes place during its ontogeny, and if this structural coupling involves the nervous system, an observer may claim that learning has taken place because he or she observes adequate behavior generated through the dynamics of states of a nervous system whose structure has been specified (selected) through experience. If, in these circumstances, the observer wants to discriminate between learned and instinctive behavior, he or she will discover that in their actual realization, both modes of behavior are equally determined in the present by the structures of the nervous system and organism, and that, in this respect, they are indeed indistinguishable. The distinction between learned and instinctive behaviors lies exclusively in the history of the establishment of the structures responsible for them.
Any description of learning in terms of the acquisition of a representation of the environment is, therefore, merely metaphorical and carries no explanatory value. Furthermore, such a description is necessarily misleading, because it implies a system in which instructive interactions would take place, and such a system is, epistemologically, out of the question. In fact, if no notion of instruction is used, the problem becomes simplified because learning, then, appears as the continuous ontogenic structural coupling of an organism to its medium through a process which follows a direction determined by the selection exerted on its changes of structure by the implementation of the behavior that it generates through the structure already selected in it by its previous plastic interactions. Accordingly, the significance that an observer may see a posteriori in a given behavior acquired through learning plays no part in the specification of the structure through which it becomes implemented. Also, although it is possible for us as human beings to stipulate from a metadomain of descriptions an aim in learning, this aim only determines a bias, a direction, in a domain of selection, not a structure to be acquired. This latter can only become specified during the actual history of learning (ontogenic structural coupling), because it is contingent on this history. A learning system has no trivial experiences (interactions) because all interactions result in a structural change, even when the selected structure leads to the stabilization of a given behavior.
Finally, to the extent that the nervous system operates as a closed neuronal network, the performance of learned or instinctive behavior as an expression of a structural coupling is always the action of a spatiotemporal network of relations of relative neuronal activities that appear to an observer
as a network of sensori-motor correlations. If the observed behavior is instinctive and is realized in an inadequate environment, the observer claims that it is instinctive behavior in a vacuum. If the observed behavior is learned and is realized in an inadequate environment, the observer calls it a mistake. In both cases, however, the situation is the same: circumstantial structural uncoupling due to operational independence between the dynamics of states of the organism and the dynamics of states of the medium, under circumstances in which their time courses for structural change do not allow structural coupling.
When two or more organisms interact recursively as structurally plastic systems, each becoming a medium for the realization of the autopoiesis of the other, the result is mutual ontogenic structural coupling. From the point of view of the observer, it is apparent that the operational effectiveness that the various modes of conduct of the structurally coupled organisms have for the realization of their autopoiesis under their reciprocal interactions is established during the history of their interactions and through their interactions. Furthermore, for an observer, the domain of interactions specified through such ontogenic structural coupling appears as a network of sequences of mutually triggering interlocked conducts that is indistinguishable from what he or she would call a consensual domain. In fact, the various conducts or behaviors involved are both arbitrary and contextual. The behaviors are arbitrary because they can have any form as long as they operate as triggering perturbations in the interactions; they are contextual because their participation in the interlocked interactions of the domain is defined only with respect to the interactions that constitute the domain. Accordingly, I shall call the domain of interlocked conducts that results from ontogenic reciprocal structural coupling between structurally plastic organisms a consensual domain (Maturana, 1975).
Once a consensual domain is established, in the same manner as occurs generally whenever there is structural coupling between several systems, any member of the coupling can be replaced by a novel system that, with respect to the structural features involved in the coupling, has the same structure. Thus, a consensual domain is closed with respect to the interlocking conducts that constitute it, but is open with respect to the organisms or systems that realize it.
What is significant for an observer in a consensual domain is that the observed organisms can be described as simultaneously existing as composite and simple unities, and, thus, as defining two nonintersecting phenomenic domains. In the first domain, the observer can describe the organisms as interacting through the properties of their components; in the second domain, he or she can describe them as interacting through their
properties as unities. In both cases, the interaction of the organisms can be described in strictly operational terms, without recourse to such semantic notions as function or meaning. Yet, when an observer communicates with another observer, he or she defines a metadomain from the perspective of which a consensual domain appears as an interlocked domain of distinctions, indications, or descriptions, according to how the observer refers to the observed behavior.
If the observer considers every distinguishable behavior as a representation of the environmental circumstances that trigger it, he or she considers the behavior as a description, and the consensual domain in which this behavior takes place as a domain of interlocked descriptions of actual environmental states that are defined through the behaviors that represent them. In this manner a description always implies an interaction. What we do as observers when we make descriptions is exactly that: We behave in an interlocked manner with other observers in a consensual domain ontogenically generated through our direct (mother-child relation) or indirect (membership in the same society) structural coupling. But if the observer forgets that the interlocked adequacy of the mutual triggering changes of state of the mutually perturbing systems in the consensual domain is the result of their ontogenic structural coupling, he or she may describe the consensual domain as if it constituted an intrinsic descriptive system in which the descriptive interactions give information to the organisms to compute the ad hoc states needed to handle the described environment. To do this is both to assume instructive interactions that for epistemological reasons are out of the question and to lose the domain of descriptions as a metadomain that exists only in a consensual domain in reference to another domain. The following considerations should make this clear.
organism and its nervous system, as well as of most (if not all) of its internal processes, in a single phenomenic domain. In fact, since the nervous system operates as a closed neuronal network in which all states of activity are relations of relative neuronal activity, all the interactions and all the changes of state of the organism (including its nervous system) that perturb the nervous system, regardless of how they arise, necessarily map in the same domain of relations of relative neuronal activities. As has been said, the result of this is the ontogenic recursive structural coupling of the structurally plastic nervous system to its own changing structure through a process in which the sequence of structural changes is determined by the sequence of structural perturbations generated either by these same structural changes, or by the interactions of the organism in its medium.
The word language comes from the Latin noun lingua, which means "tongue," and, in prior usage referred mainly to speech. By extension, however, language is now used to refer to any conventional system of symbols used in communication. A language, whether in its restricted or in its generalized form, is currently considered to be a denotative system of symbolic communication, composed of words that denote entities regardless of the domain in which these entities may exist. Denotation, however, is not a primitive operation. It requires agreement consensus for the specification of the denotant and the denoted. If denotation, therefore, is not a primitive operation, it cannot be a primitive linguistic operation, either. Language must arise as a result of something else that does not require denotation for its establishment, but that gives rise to language with all its implications as a trivial necessary result. This fundamental process is ontogenic structural coupling, which results in the establishment of a consensual domain.
Within a consensual domain the various components of a consensual interaction do not operate as denotants; at most, an observer could say that they connote the states of the participants as they trigger each other in interlocked sequences of changes of state. Denotation arises only in a metadomain as an a posteriori commentary made by the observer about the consequences of operation of the interacting systems. If the primary operation for the establishment of a linguistic domain is ontogenic structural coupling, then the primary conditions for the development of language are, in principle, common to all autopoietic systems to the extent that they are structurally plastic and can undergo recursive interactions.
Linguistic behavior is behavior in a consensual domain. When linguistic behavior takes place recursively, in a second-order consensual domain, in such a manner that the components of the consensual behavior are recursively combined in the generation of new components of the consen-
sual domain, a language is established. The richness attained by a language throughout its history, therefore, depends necessarily both on the diversity of behaviors that can be generated and distinguished by the organisms that participate in the consensual domain, and on the actual historical realization of such behaviors and distinctions. The various failures and successes attained in the attempts to generate a linguistic domain of interactions with chimpanzees illustrate this point (Linden, 1978). In fact, whenever an attempt has been made to couple a sufficiently diversified domain of arbitrary distinctions that both the chimpanzee and the observer could make (such as visual or manual distinctions) to an at least commensurable domain of non-arbitrary distinctions (biologically significant) again common to both, an expanding linguistic domain could indeed be developed. Conversely, when the attempt was to couple two domains of distinctions whose varieties did not match in the chimpanzee and the observer) no expanding linguistic domain could be developed. The sign language of the deaf is another illustration of these points.
Since I have not mentioned grammar or syntax in this characterization of language, the following comments are necessary.
phic could some isomorphism be expected in the physiology of similarly behaving organisms that participate in a consensual domain. Such a coincidence, however, would be a matter of historical contingency, not of structural necessity.
consensual domain, or because some independent intercurrent interaction occurs that leads them out of the consensual domain.
What happens in a linguistic interaction, therefore, depends strictly on the structural state of the organism undergoing the interaction. For an observer who does not know the structural states of the linguistically interacting organisms, the outcome of a particular linguistic interaction may seem ambiguous, as if the actual syntactic value of a particular linguistic conduct were determined by some internal, not apparent, rule. Yet for each of the actual linguistically interacting organisms there is no such ambiguity. Their internal structure, as the structural background on which their linguistic interactions operate as triggering perturbations, is at any moment determined by their previous interactions and by their previous independent structural dynamics in a non ambiguous manner. Therefore, the context on which the outcome of a linguistic interaction depends is completely determined in the structure of the interacting organisms, even if this is unknown to the observer. The overheard sentence, "They are flying planes," is ambiguous only for the observer who wants to predict the outcome of the interaction with insufficient knowledge of the structural state of the speaking organism. The question in the mind of an observing linguist would be: "How can I determine the superficial syntactic value of the components of the sentence if I do not know its deep structure that determines its effective surface structure, or if I do not know the semantic value of the sentence that, by determining its deep structure, determines its surface syntax?" In fact, this question is irrelevant; it does not refer to the processes that take place in the linguistic interactions and that determine their outcome in the consensual domain. Superficial and deep syntactic structures are features of one descriptions of linguistic utterances, not of the processes of their generation.
organisms through their structural coupling in a domain of expanding ambient diversity.
The task of an observer who faces a problem in communication is either to design a system with emitter and receiver components connected via a conducting element, such that for every distinguishable state produced in the emitter a single distinguishable state is generated in the receiver, or to treat a preexisting system as if it operated like this. Since instructive interactions do not take place in the operational domains that we are considering, the emitter and receiver must be operationally congruent for the phenomenon of communication to occur. In other words, the domain of possible states of the emitter and the domain of possible states of the receiver must be homomorphic, so that each state of the emitter triggers a unique state in the receiver. If the communication system is designed by the observer, this homomorphism is obtained by construction; if a preexisting system is described as a communication system by the observer he or she assumes this homomorphism in his or her description. In fact, every interaction can be trivially described as a communication. Therefore, it must be understood that the current view of communication as a situation in which the interacting systems specify each other's states through the transmission of information is either erroneous or misleading. If this view assumes that instructive interactions take place, it is erroneous; if this view is only meant as a metaphor, it is misleading because it suggests models that imply instructive interactions. Such errors frequently occur in attempts to explain the semantic role of language.
From all these considerations, it is apparent that an established linguistic domain is a system of communication that reflects a behavioral homomorphism resulting from structural coupling. in other words, linguistic communication always takes place after the establishment of an ontogenic structural coupling, and in that sense is trivial because it shows only that the engineer's situation has been established. What is not trivial, however, is what takes place in the process of attaining communication through the establishment of ontogenic structural coupling and the shaping of the consensual domain. During this process there is no behavioral homomorphism between the interacting organisms and, although individually they operate strictly as structure-determined systems, everything that takes place through their interactions is novel, anti-communicative, in the system that they then constitute together, even if they otherwise participate in other consensual domains. If this process leads to a consensual domain, it is, in the strict
sense, a conversation, a turning around together in such a manner that all participants undergo nontrivial structural changes until a behavioral homomorphism is established and communication takes place. These pre-communicative or anti-communicative interactions that take place during a conversation, then, are creative interactions that lead to novel behavior. The conditions under which a conversation takes place (common interest, spatial confinement, friendship, love, or whatever keeps the organisms together), and which determine that the organisms should continue to interact until a consensual domain is established, constitute the domain in which selection for the ontogenic structural coupling takes place. Without them, a consensual domain could never be established, and communication, as the coordination of noncreative ontogenically acquired modes of behavior, would never take place.
The word reality comes from the Latin noun res, meaning "thing." The fundamental operation that an observer can perform is an operation of distinction, the specification of an entity by operationally cleaving it from a background. Furthermore, that which results from an operation of distinction and can thus be distinguished, is a thing with the properties that the operation of distinction specifies, and which exists in the space that these properties establish. Reality, therefore, is the domain of things, and, in this sense, that which can be distinguished is real. Thus stated, there is no question about what reality is: It is a domain specified by the operations of the observer. The question that remains is a question in the domain of cognition: It is a question about objectivity. In other words, to paraphrase the questions presented at the beginning, "How is it that we, human beings, can talk about things, describe things, and predict events in terms of things to be observed?"
After all that I have said throughout this chapter, the answer to this question should be unambiguous. Yet let me recapitulate, as an observer, the essence of what I have said.
First, the epistemological analysis of our operation as scientists showed that all scientific statements are necessarily subject-dependent, even these that I am making now as a scientist writing about the problem of objectivity.
Second, the analysis of the organization of the living and the nervous systems showed: (a) both are closed systems and, accordingly, do not offer means for the description of an objective reality; and (b) that the effective operation of a living system (nervous system included) in the medium in
which it is realized (as an autopoietic unity) is the result of its structural coupling to that medium.
Third, the analysis of language showed: (a) that language exists in a consensual domain generated by the interactions of closed systems and not in the domain of states of each individual system; and (b) that a description always implies an interaction of the system that describes. Let us now as author and reader, adopt the roles of super-observers and answer two questions, which again are reformulations of the questions presented at the beginning:
Human beings can talk about things because they generate the things they talk about by talking about them. That is, human beings can talk about things because they generate them by making distinctions that specify them in a consensual domain, and because, operationally, talking takes place in the same phenomenic domain in which things are defined as relations of relative neuronal activities in a closed neuronal network. In other words, for us as super-observers, it is apparent that human beings can talk about only that which they can specify through their operations of distinction, and that as structure-determined systems, they can only make distinctions that their structural coupling to their medium (other organisms included) permits. Accordingly, the changes of state that human beings or their instruments undergo in their interactions constitute the specification and description of the things entered as elements in their consensual domains, and this occurs under conditions in which their changes of state are determined by their structures and their structures are the result of their structural couplings. Obviously, this result is possible because, although every internal or external interaction of an organism is mapped in the relations of relative neuronal activities of its nervous system, where they cannot be distinguished as individual experiences, they can be distinguished socially in terms of be-
havior within a consensual domain. As a consequence, although descriptions ultimately always imply interactions of the organism through its components, language permits descriptions of entities in as many different domains as can be defined consensually, however removed from actual interactions they may seem to an observer, because linguistic descriptions always take place as consensual distinctions of relations of relative neuronal activities in the talking organisms, and consensual distinctions always imply interactions between organisms through their components. Thus, talking human beings dwell in two nonintersecting phenomenal domains: the domain of their internal states and the domain of their interactions in the consensual domain. Since these two domains are nonintersecting, neither can be reduced to the other, even though an observer can establish a homomorphism between them. This is obvious for me as a super-observer because I am external to both. For the human being talking, however, all that exists is his or her domain of experiences (internal states) on which everything is mapped, and the human being operates through experiences as if a phenomenal reduction had taken place. Yet, if he or she could be led to become a super-observer, he or she would accept the legitimacy of these multiple, nonintersecting phenomenal domains in which he or she can operate without demanding reductionist explanations.
In synthesis, although many spaces can be described through language, no space can be described that cannot be mapped onto the changes of state of the linguistically interacting organisms through the interactions of their components. Therefore, the ultimate and basic space that a composite unity can describe in a consensual domain is the space in which its components exist; the space in which its components exist determines the ultimate domain of interactions through which a composite unity can participate in the generation of a consensual domain. Thus, the human domain of descriptions is both bounded and unlimited. It is bounded, because every description that a human being makes necessarily implies an interaction through his components; it is unlimited, because through the operation of the nervous system the person can always recursively refine new phenomenic domains through the consensual specification of new unities composed through the coupling of old ones. In general, then, the ultimate space that the components of a composite system define is for such a system its ground space. Men, in particular, specify their ground space, the space which they define as composite unities by describing their components through their interactions through their components, as the physical space. As a consequence/ the human cognitive domain, the human domain of descriptions, is necessarily closed: every human assertion implies an interaction. That about which man cannot talk he cannot speak.
First, it is apparent that if, for the organisms that possess a natural language, to enact it is to realize their autopoiesis through their behavior in a consensual domain, then effective linguistic interactions between organisms (linguistic interactions that lead to their continued operation within the consensual domain without loss of autopoiesis) are necessarily an expression of (a) their reciprocal structural coupling; and (b) the changes in relations of relative neuronal activities in their respective nervous systems as determined by their structures and selected by their interactions.
Second, from the perspective of an observer, it is apparent that the relations of relative neuronal activities that take place in the nervous system of an organism that participates in a consensual domain result either from its structural coupling to the other members of the consensual domain, and represent (for the observer) external interactions, or from the recursive structural coupling of the nervous system to its own structure, and represent (for the observer) internal interactions. Relations of the first kind correspond to things distinguished in a consensual, social, domain; whereas relations of the second kind correspond to things distinguished in a private, personal domain that may or may not intersect with the social domain. The first correspond to experiences that pertain to a consensual reality, the second to experiences that pertain to a private, individual reality. In these circumstances, since a prediction is the realization in a consensual domain of a state in a model, and since the operation within a consensual domain as well as all the external and internal interactions of an organism involving its nervous system are equally realized as configurations of changing relations of relative neuronal activities in its nervous system, a prediction cannot but correspond to a configuration of relations of relative neuronal activities to be obtained if certain operations (other relations of relative neuronal activities) are realized. If the operations to be realized arise from relations of relative neuronal activities that correspond to external interactions, then the prediction belongs to the domain of consensual reality; if the operations to be realized arise from relations of relative neuronal activities that correspond to internal interactions, then the prediction belongs to the domain of private reality. In either case, however, predictions are realized as actual experiences, that is, as actual states of the organisms obtained through the realization of the operations that constitute the predictions if the organisms operate within the domains of structural couplings in which the predictions are made. In other words, the realization of a prediction in a consensual domain is a necessary result of the structural coupling that constitutes the consensual domain. Only if it implies operations outside the consensual domain in
which it is made is a prediction not fulfilled. The operation of a structure determined system is necessarily perfect; that is, it follows a course determined only by neighborhood relations in its structure and by nothing else. It is only in a referential domain, such as the domain of behavior, that an observer can claim that an error has occurred when his or her expectations are not fulfilled because, contrary to them, the operation of the organism reveals that it is not structurally coupled to the medium in which he or she observes it and in which he or she predicts its behavior.
These answers made by a human observer in the role of superobserver also apply to his or her own operation as an observer, because the operation of an observer is an operation in a second-order consensual domain. Accordingly, although we have played the role of superobservers in order to reveal the manner of operation of linguistic interactions, no human being can effectively operate as an absolute superobserver, because of the closure of his domain of descriptions. This, however, does not weaken the argument, which remains fully valid after collapsing the superobserver into the observer, because it is based only on relations proper to a second-order consensual domain that permit an observer to play such a role: the role of a second-order observer, the observer of the observer in its medium.
We live in a domain of subject-dependent realities, and this condition is the necessary result of our being structure-determined, closed, autopoietic systems. Yet we are not like the chained men in the cave of Plato's Republic who saw only the shadows of objective entities that could, at least in principle, be conceived as having an absolute reality. We are more like pharmacologists describing biologically active substances by means of the changes of state of their biological probes. There is no similarity between the changes of state that a female rabbit undergoes and the hormone that brings them about; nobody claims that there is. However, strictly, for a long time and in the absence of other methods, many substances have been characterized by the changes of state of the biological probes that revealed them. Furthermore, other methods are not effectively different from the pharmacological one. This is not a novelty. Yet it is not frequently realized, and it is less frequently taken seriously in the domain of science, that we human beings operate in our cognitive domain like the pharmacologist and that we can only operate in this way by using ourselves as biological probes with which we specify and describe the domains of reality in which we live. That we should be living systems is obviously not a necessary condition, but it is an existential condition that determines how our domains of reality are
generated; because in us, as in all living systems, all operations are subordinated to the invariance of our autopoiesis.
The extent of what an organism can do is determined by its organization and structure, and all that an organism can do constitutes its cognitive domain. The way we (human beings) determine knowledge shows that implicitly or explicitly we accept this to be the case: We ask a question in a given domain and, as an answer we expect an action, or the description of an action, in the same domain. The fact that we usually demand that human beings should be aware of their knowledge -- that is, that they should be observers -- does not change the matter. Our cognitive domain is bounded and unlimited in the same manner in which our domain of reality is bounded and unlimited. Knowledge implies interactions, and we cannot step out of our domain of interactions, which is closed. We live, therefore, in a domain of subject-dependent knowledge and subject-dependent reality. This means that if the questions, "What is the object of knowledge?" or "What is the objective reality of an object?" are meant to be answered by an absolute observer, then they are meaningless, because such an absolute observer is intrinsically impossible in our cognitive domain. In fact, any knowledge of a transcendental absolute reality is intrinsically impossible; if a supposed transcendental reality were to become accessible to description then it would not be transcendental, because a description always implies interactions and, hence, reveals only a subject-dependent reality. The most we can say, therefore, is that the observer generates a description of the domain of reality through his or her interactions (including interactions with instruments and through instruments), and that the observer can describe a system of systems (a system of consensus) that leads to the emergence of systems that can describe: observers. As a consequence, because the domain of descriptions is closed, the observer can make the following ontological statement: The logic of the description is isomorphic to the logic of the operation of the describing system.
Apparently all that remains is the observer. Yet the observer does not exist alone, because his existence necessarily entails at least an other being as a necessary condition for the establishment of the consensual domain in which he exists as an observer. However, what is unique to each observer and makes each observer stand alone, is, on the one hand, his or her experiences, which remain necessarily secluded in his or her operational
closure, and, on the other hand, the observer's ability through second-order consensuality to operate as external to the situation in which he or she is, and thus be observer of his or hers circumstance as an observer.
Much of what I have said has been intuitively accepted by philosophers since antiquity, but until now no one had proposed an explanation that could show the biological nature of the phenomena of cognition and reality. This chapter is such an explicit attempt (see also Maturana, 1970, 1974). Furthermore, until now, it had not been shown that there is no contradiction between the subject-dependent nature of our reality and our effective operation in a socially valid and seemingly objective physical world. Since a description always implies an interaction, and since the describing systems describe their components via their interactions through their components, there is a constitutive homomorphism between descriptions, and behavior in general, and the operation of the systems that describe. Therefore, we literally create the world in which we live by living it. If a distinction is not performed, the entity that this distinction would specify does not exist; when a distinction is performed, the created entity exists in the domain of the distinction only, regardless of how the distinction is performed. There is no other kind of existence for such an entity.
In this context, then, what are creativity and freedom?
Answers to these questions have been entangled in a frequent confusion of determinisms with predictability, and in the belief in the objective occurrence of the phenomenon of choice. That a system is structure determined means that it is deterministic and that in its operation choice is out of the question, but it does not mean that it is necessarily predictable. Determinism is a feature of the operation of a system, while predictability and choice are expressions that reflect the state of knowledge of the observer. If the system observed and the medium in which it is observed are known, then the system does not appear to encounter alternatives in its interactions, because it and its medium form for the observer a single predictable system; if the system or the medium are unknown, then the system appears to encounter alternatives in its interactions, because system and medium constitute operationally independent systems for the observer who cannot predict their course: in such a case the observer projects his or her own uncertainty on the system by claiming that it must make a choice. An unknown system is, for the ignorant observer, a chaos, however deterministic it may appear to the knowing observer who sees it as a structure-determined system. Once
this is understood, it becomes apparent that a novelty, the new, is always an event viewed in a frame of reference from which it could not have been predicted by an observer.
When an organism enters into an interaction that arises from a contingency, that is, from an encounter with an operationally independent system (which could be part of the organism itself), the ensuing triggered changes of state of the organism could not have been predicted by an observer of the operation of the organism alone. For the observer, the organism performs a novel distinction and specifies a new reality. This is creativity: the generation by an organism of distinctions (unexpected for an observer) through its interactions with systems to which it is not structurally coupled (operationally independent systems), and to which it may become structurally coupled as a result of the interactions. Since the structure of an organism (its nervous system included) is under continuous change as a result of its autopoiesis in an operationally independent medium, organisms are, at least potentially, in the position of undergoing a continuous change in their structural couplings anal hence, of continuously encountering independent systems and thus of undergoing continuous changes of state unpredictable from their perspective alone. Creativity, then, is a necessarily widespread feature in living systems.
If an organism exists in a domain that does not determine all its interactions, so that it can undergo interactions with independent systems, there is freedom in the domain of existence of the organism. The organism is free even if its operation is deterministic, and if it can generate second-order consensual domains, it can, as an observer, recursively generate operationally independent consensual entities as a recursive observer of its circumstance. This has been well understood throughout the history of mankind. If a human being can observe the social system that he creates with his behavior, he may dislike it and reject it, and thus become a source of change, but if he can only undergo interactions specified by the social system that he integrates, he cannot be an observer of it and his behavior can only confirm it. Accordingly, all coercive political systems aim, explicitly or implicitly, at reducing creativity and freedom by specifying all social interactions as the best means of suppressing human beings as observers and thus attaining political permanence. To obtain this ultimate goal, however, the typically human mode of creativity must be completely suppressed, and this, as long as there is any capacity to establish such second-order consensual domains as the use of language requires, is impossible.
Every human being, as an autopoietic system, stands alone. Yet let us not lament that we must exist in a subject-dependent reality. Life is more interesting like this, because the only transcendence of our individual lone-
liness that we can experience arises through the consensual reality that we create with others, that is, through love.
I wish to acknowledge my indebtedness to Gloria Guiloff D., my close collaborator, to whom I owe the most fundamental insight here given, namely, the understanding of the consensual domains.
Edelman, G. M. Molecular recognition in the immune and nervous systems. In F. G. Worden, J. P. Swazey, & G. Adelman (Eds.), The neurosciences: paths of discovery. Cambridge: MIT Press, 1975.